
Seasonal Guide: Best Times to Travel Different Sections of Route 66
Route 66, the iconic American highway stretching from Chicago to Los Angeles, offers diverse experiences across its nearly 2,500-mile length. This guide will help you plan the best times to travel different sections of the Mother Road based on weather, events, and attractions.
1. Illinois and Missouri (Chicago to St. Louis)
Best time to visit: Late spring (May-June) or early fall (September-October)
- Avoid the humid summers and harsh winters of the Midwest
- Spring brings blooming flowers along the route
- Fall offers beautiful autumn colors and pleasant temperatures
- Notable events:
- Route 66 Festival in Springfield, IL (September)
- St. Louis Blues Festival (September)
2. Kansas, Oklahoma, and Texas Panhandle
Best time to visit: April-May or September-October
- Spring and fall offer mild temperatures and lower chances of severe weather
- Avoid summer for its intense heat and potential for tornadoes
- Winter can bring unexpected snowstorms
- Notable events:
- Oklahoma Route 66 Museum’s Anniversary Celebration (September)
- Tulsa Oktoberfest (October)

3. New Mexico
Best time to visit: March-May or September-November
- Spring and fall provide comfortable temperatures and clear skies
- Summer can be extremely hot, especially in the southern parts
- Winter brings snow to higher elevations but can be a magical time in places like Santa Fe
- Notable events:
- Albuquerque International Balloon Fiesta (October)
- Santa Fe Indian Market (August)
4. Arizona
Best time to visit: March-May or October-November
- Spring and fall offer pleasant temperatures for exploring outdoor attractions
- Avoid summer due to extreme heat, especially in desert areas
- Winter can be ideal for southern Arizona but may bring snow to northern parts like Flagstaff
- Notable events:
- Historic Route 66 Fun Run (May)
- Standin’ on the Corner Festival in Winslow (September)
5. California
Best time to visit: April-May or September-October
- Spring and fall provide mild temperatures across the state
- Summer can be very hot in inland areas but pleasant along the coast
- Winter brings cooler temperatures and potential for rain, but can be a great time to visit desert areas
- Notable events:
- Route 66 Cruisin’ Reunion in Ontario (September)
- Santa Monica Pier Summer Concert Series (July-August)
General Tips:
- Flexibility is key: Weather can be unpredictable, so be prepared to adjust your plans.
- Off-season travel: Consider traveling in shoulder seasons for fewer crowds and lower prices.
- Local events: Research local festivals and events along your route to enhance your experience.
- Road conditions: Check road conditions, especially in winter or during severe weather seasons.
- Attractions schedule: Some attractions may have limited hours or be closed during off-seasons, so always verify operating hours in advance.
Remember, each season offers its own unique charm along Route 66. Whether you’re chasing the perfect road trip weather or hoping to catch specific events, planning your journey with the seasons in mind will help you make the most of your Route 66 adventure.